Product Overview

L-Valine is an essential branched-chain amino acid produced through microbial fermentation for food, nutrition, and pharmaceutical applications.

Technical Specifications

Category	Specification Item	Test Method / Reference
Physical & Chemical Properties	Appearance	Visual
	Odor & Taste	Organoleptic
	Solubility	USP / EP
	pH Value	pH Meter (5% w/v solution)
Purity & Quality	Assay (Dried Basis)	Titration (USP/EP)
	Specific Optical Rotation [α]D20	Polarimeter (C = 8, 6M HCl)
	State of Solution (Transmittance)	Spectrophotometer (430 nm)
	Loss on Drying	Gravimetric (105°C, 3 h)
	Residue on Ignition (Sulfated Ash)	Gravimetric
	Chloride (Cl⁻)	Volumetric
	Sulfate (SO₄²⁻)	Turbidimetric
	Ammonium (NH₄⁺)	Colorimetric
	Iron (Fe)	Atomic Absorption
	Other Amino Acids / Impurities	TLC / HPLC
Heavy Metals & Contaminants	Lead (Pb)	ICP-MS
	Arsenic (As)	ICP-MS
	Cadmium (Cd)	ICP-MS
	Mercury (Hg)	ICP-MS
Microbiological Limits	Total Aerobic Microbial Count (TAMC)	USP <61> / EP 2.6.12
	Total Yeasts & Molds Count (TYMC)	USP <61> / EP 2.6.12
	E. coli	USP <62> / EP 2.6.13
	Salmonella	USP <62> / EP 2.6.13
	Coliforms	USP <62> / EP 2.6.13
	Bacterial Endotoxins*	LAL Test (USP <85>)

Standards Compliance: Product specifications are established in accordance with USP and EP purity requirements.

Impurity Profiling: HPLC testing monitors individual amino acid impurity levels according to specification limits.

Heavy Metals: ICP-MS testing limits lead to below 3 ppm to meet regulatory specifications.

Microbiological Safety: Microbiological monitoring is conducted according to established specification limits.

Targeted Fermentation Scale
Dedicated bioreactors utilize production strains for L-Valine fermentation.

Branched-Chain Separation
Ion-exchange chromatography is used during amino acid purification.

Microbial Biomass Removal
Membrane filtration is applied during downstream purification processes.

Feedstock Risk Mitigation
Multiple sourcing channels support raw material supply continuity.

Application Sector	Application Description
Animal Nutrition	Blended into low-protein swine and poultry diets.
Pharmaceuticals	Formulated into intravenous amino acid infusion solutions.
Sports Nutrition	Combined with leucine and isoleucine in BCAA powders.
Medical Nutrition	Integrated into enteral nutrition formulas for hepatic patients.
Fermentation Media	Added as a nitrogen substrate in biopharmaceutical cell cultures.

Moisture-Barrier Drumming
Food and pharmaceutical grades are packed in fiber drums with heat-sealed double PE inner liners.

Bulk Woven Bagging
Industrial and feed grades are packed in multi-wall laminated bags against moisture.

Static-Dissipative Liners
Anti-static inner liners help minimize electrostatic buildup during powder discharge operations.

Sealed Container Desiccant
Shipping containers incorporate high-capacity desiccant pouches to help control moisture during ocean transit.

Temperature-Controlled Shipping
Reefer container options are available when temperature-controlled transportation is required.

Q: What is the primary botanical or chemical origin of the raw materials used for L-Valine synthesis?

A: Production utilizes plant-derived glucose as the primary fermentation substrate.

Q: How does the factory manage potential cross-contamination with other branched-chain amino acids during processing?

A: Equipment cleaning procedures and production controls help reduce cross-contact risks.

Q: What specific documentation is provided to clear international customs for regulated food applications?

A: Documentation may include COA, origin certificates, allergen statements, and non-GMO declarations.

Q: Can the material be adjusted to meet specific particle size requirements for specialized tableting processes?

A: Particle size specifications can be adjusted according to application requirements.

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