Glycine

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Glycine
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Glycine is a non-essential amino acid serving as a proteinogenic building block and functional intermediate in food, pharmaceutical and industrial applications.
Category
Amino Acid
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Description

Product Overview

 

Glycine is a non-essential amino acid serving as a proteinogenic building block and functional intermediate in food, pharmaceutical and industrial applications.

 

Technical Specifications

 

Category

Parameter / Test Item

Specification Limit

Core Purity & Assays

Assay (on dried basis)

98.5% – 101.5%

pH (5% Aqueous Solution)

5.5 – 6.5

Clarity and Color of Solution

Clear and colorless (A430 ≤ 0.010)

Process-Specific Impurities

Monochloroacetic Acid (MCAA)

≤ 5 ppm

Iminodiacetic Acid (IDA)

≤ 0.1%

Glycine Anhydride

≤ 0.1%

Inorganic & Purity Controls

Loss on Drying

≤ 0.2%

Residue on Ignition / Sulfated Ash

≤ 0.1%

Chloride (as Cl)

≤ 0.007% (≤ 70 ppm)

Sulfate (as SO₄)

≤ 0.0065% (≤ 65 ppm)

Ammonium (as NH₄)

≤ 0.02%

Heavy Metals Control

Lead (Pb)

≤ 1.0 ppm

Arsenic (As)

≤ 1.0 ppm

Cadmium (Cd)

≤ 0.5 ppm

Mercury (Hg)

≤ 0.1 ppm

Microbiological Limits

Total Plate Count

≤ 1,000 cfu/g

Molds & Yeasts

≤ 100 cfu/g

E. coli & Salmonella

Negative

Physical & Handling

Mesh Sizing (Standard Crystalline)

20 – 80 mesh (Customizable)

Bulk Density

0.85 – 1.05 g/mL

 

Synthesis & Manufacturing Control

 

Synthesis Pathway Regulation
Dosing systems control chloroacetic acid and ammonia feed rates during synthesis.

 

Amination Temperature Stabilization
Cooling systems control reaction temperatures during amination processing.

 

Ammonium Chloride Segregation
Multi-stage crystallization separates inorganic salts from the refined Glycine stream.

 

Decolorization Carbon Filtration
Fixed-bed activated carbon columns remove reaction pigments to ensure solution clarity.

 

Quality Assurances & Compliance

 

MCAA Residual Quantification
GC-MS testing confirms monochloroacetic acid (MCAA) levels remain below 5 ppm.

 

Iminodiacetic Acid Assays
HPLC analysis monitors iminodiacetic acid (IDA) impurity levels.

 

Chloride Ion Argentometry
Potentiometric titration tracks trace chloride levels to meet electroplating grade specifications.

 

Crystalline Moisture Profiling
Loss-on-drying testing monitors moisture levels against specification limits.

 

Supply Chain & Packaging Reliability

 

Zwitterionic Compaction Prevention
Temperature and humidity controlled storage helps reduce crystal caking during storage.

 

Double-Layer HDPE Barriers
Automated packaging seals Glycine in double-layer HDPE liners to block moisture.

 

Nitrogen-Purged Bulk Silos
Bulk silos utilize nitrogen blanketing to reduce moisture exposure.

 

Buffer Stock Management
Regional warehouses maintain inventory levels to support shipment planning.

 

Seaworthy Desiccant Layouts
Shipping containers utilize calcium chloride desiccants to manage moisture during ocean transit.

 

FAQ

 

Q: Can heavy metal test reports be provided with shipments?

A: Yes, analytical reports can be supplied according to customer requirements.

Q: How is Glycine protected from moisture during ocean transportation?

A: Moisture-barrier packaging and desiccants are used during shipment.

Q: How is product consistency monitored during production?

A: Process controls and routine testing support batch consistency.

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